Tributyl(4-fluorophenyl)stannane → [2-(4-fluorophenyl)-5,7-dihydropyrrolo[3,4-b]pyridin-6-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone

HRID 200955Notes

Reaction equation

HRID 200955 reaction equation
[CH2:30]([Sn:31]([CH2:32][CH2:33][CH2:34][CH3:42])([c:35]1[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]1)[CH2:43][CH2:44][CH2:45][CH3:46])[CH2:47][CH2:48][CH3:49].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[CH2:8][N:9]([C:11](=[O:12])[c:13]1[c:14]([O:23][CH:24]([C:25]([F:26])([F:27])[F:28])[CH3:29])[cH:15][cH:16][c:17]([S:19](=[O:20])(=[O:21])[CH3:22])[cH:18]1)[CH2:10]2>>[c:2]1(-[c:35]2[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]2)[cH:3][cH:4][c:5]2[c:6]([n:7]1)[CH2:8][N:9]([C:11](=[O:12])[c:13]1[c:14]([O:23][CH:24]([C:25]([F:26])([F:27])[F:28])[CH3:29])[cH:15][cH:16][c:17]([S:19](=[O:20])(=[O:21])[CH3:22])[cH:18]1)[CH2:10]2

Participants

3

Reactant 2

HCID 2737524Tributyl(4-fluorophenyl)stannaneHCID 88271562(2-Chloro-5,7-dihydropyrrolo[3,4-b]pyridin-6-yl)-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone

Product 1

HCID 178466854[2-(4-fluorophenyl)-5,7-dihydropyrrolo[3,4-b]pyridin-6-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone

Sources & evidence

ORD record
ord-81e5ed64dcf744ae87e0d48280ad8a1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…