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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010173Generated: November 4, 2026

ethyl 3-bromo-1-(1-ethoxyethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylate → ethyl 1H-thieno[2,3-c]pyrazole-5-carboxylate

https://huagongshe.com/reaction/2010173

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl 3-bromo-1-(1-ethoxyethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylateHCID 57487832—
ReagentDiisopropylethylamineHCID 81531—
CatalystZincHCID 23994—
SolventMethanolHCID 887—
Productethyl 1H-thieno[2,3-c]pyrazole-5-carboxylateHCID 141152679—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-74453e8534d44e3eb501a28f96349064
Source note39k HTE dataset from Pfizer