Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010590Generated: October 30, 2026

6-Bromoquinoline → 6-Pyridin-2-ylquinoline

https://huagongshe.com/reaction/2010590

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantSodium Pyridine-2-sulfinateHCID 23678794—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalyst2'-(diphenylphosphanyl)-N,N-dimethyl-[1,1'-biphenyl]-2-amineHCID 2734939—
CatalystHCID 178483775HCID 178483775—
Solvent2-Methyl-2-butanolHCID 6405—
Product6-Pyridin-2-ylquinolineHCID 69036820—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-d2537e43e4734ad7a33f6e02702f4041
Source note39k HTE dataset from Pfizer