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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010741Generated: October 30, 2026

6-Bromoquinoline → 6-Pyridin-2-ylquinoline

https://huagongshe.com/reaction/2010741

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantSodium Pyridine-2-sulfinateHCID 23678794—
ReagentWaterHCID 962—
ReagentPotassium Phosphate, TribasicHCID 62657—
CatalystBis(cyclopentyl(diphenyl)phosphane);ironHCID 24721398—
CatalystHCID 178483775HCID 178483775—
Solvent2-Methyl-2-butanolHCID 6405—
Product6-Pyridin-2-ylquinolineHCID 69036820—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-9d06f4b494914b4fb39beec6a09b3b50
Source note39k HTE dataset from Pfizer