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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010778Generated: October 30, 2026

6-Bromoquinoline → 6-Pyridin-2-ylquinoline

https://huagongshe.com/reaction/2010778

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantSodium Pyridine-2-sulfinateHCID 23678794—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalyst2-(2,6-Dimethylphenylamino)-2-oxoacetic acidHCID 14987869—
CatalystHCID 178483775HCID 178483775—
SolventTetrahydrofuranHCID 8028—
Product6-Pyridin-2-ylquinolineHCID 69036820—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-e3c949ea434d441e9689cd19dc4fea6d
Source note39k HTE dataset from Pfizer