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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010791Generated: October 29, 2026

6-Bromoquinoline → 6-Pyridin-2-ylquinoline

https://huagongshe.com/reaction/2010791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantSodium Pyridine-2-sulfinateHCID 23678794—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalyst(1,1'-Binaphthalen)-2-yldi-tert-butylphosphineHCID 2734941—
CatalystHCID 178483775HCID 178483775—
SolventAcetonitrileHCID 6342—
Product6-Pyridin-2-ylquinolineHCID 69036820—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-d817851edd0b470a9fe8e9d2c6c8f085
Source note39k HTE dataset from Pfizer