Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2010832Generated: October 29, 2026

6-Bromoquinoline → 6-Pyridin-2-ylquinoline

https://huagongshe.com/reaction/2010832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantSodium Pyridine-2-sulfinateHCID 23678794—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalyst(Pentane-1,5-diyl)bis(di-tert-butylphosphane)HCID 611933—
CatalystHCID 178483775HCID 178483775—
SolventTolueneHCID 1140—
Product6-Pyridin-2-ylquinolineHCID 69036820—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-86677deb35df4818b385aefbd2102c1c
Source note39k HTE dataset from Pfizer