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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 201103Generated: October 29, 2026

Sodium ion → 8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-methoxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrile

https://huagongshe.com/reaction/201103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantMethyl iodideHCID 6328—
Reactant18-Crown-6HCID 28557—
ReactantHydrideHCID 166653—
Reactant8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrileHCID 88039642—
Product8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-methoxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrileHCID 88039608—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-ce8f9e87ad424c449715837b10e1fdf5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)