N-(3-methoxyphenyl)piperazine → Methyl {2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrido[3,4-d]pyrimidin-4-yl}acetate

HRID 201203Notes

Reaction equation

HRID 201203 reaction equation
[CH3:26][O:27][c:28]1[cH:29][c:30]([N:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[cH:31][cH:32][cH:33]1.[F:1][C:2]([c:3]1[cH:4][c:5]([N:9]=[C:10]=[N:11][c:12]2[cH:13][n:14][cH:15][cH:16][c:17]2[CH:18]=[CH:19][C:20](=[O:21])[O:22][CH3:23])[cH:6][cH:7][cH:8]1)([F:24])[F:25]>>[F:1][C:2]([c:3]1[cH:4][c:5]([N:9]2[C:10]([N:37]3[CH2:36][CH2:35][N:34]([c:30]4[cH:29][c:28]([O:27][CH3:26])[cH:33][cH:32][cH:31]4)[CH2:39][CH2:38]3)=[N:11][c:12]3[cH:13][n:14][cH:15][cH:16][c:17]3[CH:18]2[CH2:19][C:20](=[O:21])[O:22][CH3:23])[cH:6][cH:7][cH:8]1)([F:24])[F:25]

Participants

3

Reactant 2

HCID 81430N-(3-methoxyphenyl)piperazineHCID 90761513Methyl 3-[3-[[3-(trifluoromethyl)phenyl]iminomethylideneamino]-4-pyridinyl]prop-2-enoate

Product 1

HCID 59168068Methyl {2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrido[3,4-d]pyrimidin-4-yl}acetate

Sources & evidence

ORD record
ord-01339b77ccc847dbb40c39f972df93c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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