Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2012602Generated: October 31, 2026

6-Bromoquinoline → Quinoline-6-sulfonic acid

https://huagongshe.com/reaction/2012602

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
Reactant4-(Acetylamino)phenyl]imidodisulfuryl difluorideHCID 136212924—
ReagentCesium pivalateHCID 583616—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenylHCID 11155794—
SolventAcetonitrileHCID 6342—
ProductQuinoline-6-sulfonic acidHCID 316975—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3a98d6cfe88046c09f3d3cf0c83f82a6
Source note39k HTE dataset from Pfizer