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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2012697Generated: October 29, 2026

6-Bromoquinoline → Quinoline-6-sulfonic acid

https://huagongshe.com/reaction/2012697

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
Reactant4-(Acetylamino)phenyl]imidodisulfuryl difluorideHCID 136212924—
ReagentTriethylamineHCID 8471—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-Dicyclohexylphosphino-2',6'-dimethoxybiphenylHCID 11269872—
SolventDimethyl SulfoxideHCID 679—
ProductQuinoline-6-sulfonic acidHCID 316975—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-c66afd4aafb34a3a874f36020092a804
Source note39k HTE dataset from Pfizer