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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2012804Generated: October 30, 2026

6-Bromoquinoline → HCID 178454372, compound

https://huagongshe.com/reaction/2012804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantDi-tert-butyl bicarbamateHCID 85431—
Reagent2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
Catalystpalladium(II) acetateHCID 167845—
Catalyst(R)-1-[(S)-2-(Dicyclohexylphosphino)ferrocenyl]ethyli-tert-butylphosphineHCID 117064351—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178454372HCID 178454372—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-66239ffe44084977bb780cded9f2a5cf
Source note39k HTE dataset from Pfizer