HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2012987Generated: October 30, 2026
(Triethylsilyl)acetylene → 5-Chloro-3-(triethyl-silanylethynyl)-pyrazin-2-ylamine
https://huagongshe.com/reaction/2012987
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (Triethylsilyl)acetylene | HCID 637947 | — |
| Reactant | 3-Bromo-5-chloropyrazin-2-amine | HCID 10488609 | — |
| Reagent | Sodium Bicarbonate | HCID 516892 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | Bis(cyclopentyl(diphenyl)phosphane);iron | HCID 24721398 | — |
| Solvent | 2-Methyltetrahydrofuran | HCID 7301 | — |
| Product | 5-Chloro-3-(triethyl-silanylethynyl)-pyrazin-2-ylamine | HCID 59463522 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-25e886855e7d415b8642e8cfc09a0e65 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
