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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013140Generated: October 27, 2026

3-Bromo-5-methylpyridine → 5-Benzyl-3-methylpyridine

https://huagongshe.com/reaction/2013140

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-methylpyridineHCID 817713—
ReactantHCID 178492747HCID 178492747—
ReagentCesium carbonateHCID 10796—
ReagentPotassium t-amylateHCID 23683543—
CatalystBinap, (A+-)-HCID 634876—
CatalystHCID 178455864HCID 178455864—
SolventGamma-ValerolactoneHCID 7921—
Product5-Benzyl-3-methylpyridineHCID 3018489—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-7357ce560a1346f2841869e6115bf2f8
Source note39k HTE dataset from Pfizer