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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013187Generated: October 26, 2026

3-Bromo-5-methylpyridine → 5-Benzyl-3-methylpyridine

https://huagongshe.com/reaction/2013187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-methylpyridineHCID 817713—
ReactantHCID 178492747HCID 178492747—
ReagentPotassium BicarbonateHCID 516893—
ReagentPotassium t-amylateHCID 23683543—
CatalystDicyclohexyl(ethyl)phosphineHCID 17909966—
CatalystHCID 178455864HCID 178455864—
Solvent1,4-DioxaneHCID 31275—
Product5-Benzyl-3-methylpyridineHCID 3018489—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-9d555bcad61d4ab78de4f01b72381871
Source note39k HTE dataset from Pfizer