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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013277Generated: October 30, 2026

3-Bromo-5-methylpyridine → 5-Benzyl-3-methylpyridine

https://huagongshe.com/reaction/2013277

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-methylpyridineHCID 817713—
ReactantHCID 178492747HCID 178492747—
ReagentPotassium BicarbonateHCID 516893—
ReagentPotassium t-amylateHCID 23683543—
Catalyst1,3-Diisopropylimidazolium chlorideHCID 11229242—
CatalystHCID 178455864HCID 178455864—
SolventPropylene CarbonateHCID 7924—
Product5-Benzyl-3-methylpyridineHCID 3018489—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-93a10b81810044b389d4fd64cc7af604
Source note39k HTE dataset from Pfizer