Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013424Generated: October 30, 2026

6-Bromoquinoline → 6-(6-Methoxypyridin-3-yl)quinoline

https://huagongshe.com/reaction/2013424

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantHCID 178492810HCID 178492810—
ReagentCesium carbonateHCID 10796—
ReagentTetrabutylammonium BromideHCID 74236—
Catalystpalladium(II) acetateHCID 167845—
Catalyst(4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphineHCID 11714598—
Solvent2-Methyl-2-butanolHCID 6405—
Product6-(6-Methoxypyridin-3-yl)quinolineHCID 122392050—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-27e89722aac54bfdab1908e0fe8a862d
Source note39k HTE dataset from Pfizer