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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013487Generated: October 29, 2026

6-Chloroquinoline → 6-(6-Methoxypyridin-3-yl)quinoline

https://huagongshe.com/reaction/2013487

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroquinolineHCID 69163—
ReactantHCID 178492810HCID 178492810—
ReagentPotassium CarbonateHCID 11430—
Catalystpalladium(II) acetateHCID 167845—
Catalyst(Pentane-1,5-diyl)bis(di-tert-butylphosphane)HCID 611933—
Solvent1,4-DioxaneHCID 31275—
Product6-(6-Methoxypyridin-3-yl)quinolineHCID 122392050—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-ebf8d746821a47139267b0106c4b6ffd
Source note39k HTE dataset from Pfizer