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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013715Generated: October 27, 2026

1-Methylimidazole → HCID 178480578, compound

https://huagongshe.com/reaction/2013715

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylimidazoleHCID 1390—
ReactantTert-butyl 4-{[(2-amino-5-bromopyridin-3-yl)oxy]methyl}piperidine-1-carboxylateHCID 121409255—
ReagentDiisopropylethylamineHCID 81531—
CatalystBis(tri-tert-butylphosphine)palladium(0)HCID 2734558—
SolventDimethylacetamideHCID 31374—
ProductHCID 178480578HCID 178480578—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-ff2e6d985af94f8a82fd61c6fa7f52d4
Source note39k HTE dataset from Pfizer