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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013742Generated: October 26, 2026

1-Methylimidazole → HCID 178480578, compound

https://huagongshe.com/reaction/2013742

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylimidazoleHCID 1390—
ReactantTert-butyl 4-{[(2-amino-5-bromopyridin-3-yl)oxy]methyl}piperidine-1-carboxylateHCID 121409255—
ReagentPotassium acetate hydrateHCID 23702041—
CatalystBis(tri-tert-butylphosphine)palladium(0)HCID 2734558—
Solvent2-Methyl-2-butanolHCID 6405—
ProductHCID 178480578HCID 178480578—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-53614075b90d427c8f0d079fede5e72d
Source note39k HTE dataset from Pfizer