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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2013766Generated: October 30, 2026

1-Methylimidazole → HCID 178480578, compound

https://huagongshe.com/reaction/2013766

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylimidazoleHCID 1390—
ReactantTert-butyl 4-{[(2-amino-5-bromopyridin-3-yl)oxy]methyl}piperidine-1-carboxylateHCID 121409255—
ReagentPotassium Phosphate, DibasicHCID 24450—
CatalystTetrakis(triphenylphosphine)palladiumHCID 11979704—
Solvent2-Methyl-2-butanolHCID 6405—
ProductHCID 178480578HCID 178480578—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3c3a0a09baef48019ad07fef0fe4b2f2
Source note39k HTE dataset from Pfizer