HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2014777Generated: October 30, 2026
7-Bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione → 3,4-Dihydro-7-(4-methyl-1H-imidazol-1-yl)pyrido[2,1-c][1,4]oxazine-1,6-dione
https://huagongshe.com/reaction/2014777
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 7-Bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione | HCID 122439902 | — |
| Reactant | HCID 178418800 | HCID 178418800 | — |
| Reagent | 2,2,6,6-Tetramethylpiperidine | HCID 13035 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | Di-tert-butyl[3,4,5,6-tetramethyl-2',4',6'-tris(propan-2-yl)-[1,1'-biphenyl]-2-yl]phosphane | HCID 11953610 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3,4-Dihydro-7-(4-methyl-1H-imidazol-1-yl)pyrido[2,1-c][1,4]oxazine-1,6-dione | HCID 68380174 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-0251f25551f741e2b246642f72f6476d |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
