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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2014797Generated: October 29, 2026

2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 178508374, compound

https://huagongshe.com/reaction/2014797

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Aminopyrimidine-5-boronic acid, pinacol esterHCID 17750212—
Reactant4-(4,6-Dichloro-5-(2-chloroethyl)pyrimidin-2-yl)morpholineHCID 56973360—
ReagentWaterHCID 962—
ReagentCesium fluorideHCID 25953—
CatalystBis(tri-o-tolylphosphine)palladium(II) DichlorideHCID 10876480—
SolventAcetonitrileHCID 6342—
ProductHCID 178508374HCID 178508374—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-a2e01f81c0534dd181ebbbffbdef3a52
Source note39k HTE dataset from Pfizer