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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2014845Generated: October 30, 2026

2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 178508374, compound

https://huagongshe.com/reaction/2014845

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Aminopyrimidine-5-boronic acid, pinacol esterHCID 17750212—
Reactant4-(4,6-Dichloro-5-(2-chloroethyl)pyrimidin-2-yl)morpholineHCID 56973360—
ReagentWaterHCID 962—
ReagentSodium HydroxideHCID 14798—
Catalyst[1,1'-bis(di-tert-butylphosphino) ferrocene]dichloropalladium(II)HCID 86278421—
SolventAcetonitrileHCID 6342—
ProductHCID 178508374HCID 178508374—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-5008110ceaa34b598ae08f0f16d7054a
Source note39k HTE dataset from Pfizer