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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2015231Generated: October 29, 2026

1,4-Dimethyl-1H-1,2,3-triazole → HCID 178434697, compound

https://huagongshe.com/reaction/2015231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dimethyl-1H-1,2,3-triazoleHCID 15257142—
Reactant7-bromo-8-chloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 118572053—
ReagentTetrabutylammonium AcetateHCID 82707—
Catalystpalladium(II) acetateHCID 167845—
Catalyst1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
Solvent2-Methyl-2-butanolHCID 6405—
ProductHCID 178434697HCID 178434697—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-bbe6f5fec9074095a68c4945c4ada4d2
Source note39k HTE dataset from Pfizer