HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Trans-[1-(2-methoxyethyl)-2-oxo-6-phenylazepan-3-yl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (trans)-Tert-butyl[1-(2-methoxyethyl)-2-oxo-6-phenylazepan-3-yl]acetate | HCID 86595045 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Trans-[1-(2-methoxyethyl)-2-oxo-6-phenylazepan-3-yl]acetic acid | HCID 66939309 | — |
Reaction Steps
Trifluoroacetic acid (1 mL) was added to a solution (trans)-tert-butyl[1-(2-methoxyethyl)-2-oxo-6-phenylazepan-3-yl]acetate (170 mg, 0.47 mmol) in dichloromethane (3 mL). After 2 h, the solution was concentrated. MS 306 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745427B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-160c60407a3b498bbc702a85afdfc69c |
| Source note | uspto-grants-2010_06 |