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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2016376Generated: October 29, 2026

6-Bromoquinoline → HCID 178454372, compound

https://huagongshe.com/reaction/2016376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
ReactantDi-tert-butyl bicarbamateHCID 85431—
ReagentLithium HexamethyldisilazideHCID 2733832—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-(Di-tert-butylphosphanyl)-1-(2-methoxyphenyl)-1H-pyrroleHCID 46919526—
Solvent2-Methyl-2-butanolHCID 6405—
ProductHCID 178454372HCID 178454372—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3dc53f1e7c8842859fe3290fd6aafc5b
Source note39k HTE dataset from Pfizer