HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2016645Generated: October 29, 2026
(R)-ethyl 1-[5-(4-iodo-1-methyl-1H-pyrazol-5-yl)-2H-tetrazol-2-yl]ethyl carbonate → tert-butyl (3R)-3-[[4-[5-[2-[(1R)-1-ethoxycarbonyloxyethyl]tetrazol-5-yl]-1-methylpyrazol-4-yl]benzoyl]-(3-methyl-2-pyridinyl)amino]piperidine-1-carboxylate
https://huagongshe.com/reaction/2016645

Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (R)-ethyl 1-[5-(4-iodo-1-methyl-1H-pyrazol-5-yl)-2H-tetrazol-2-yl]ethyl carbonate | HCID 117661191 | — |
| Reactant | Tert-butyl (R)-3-(N-(3-methylpyridin-2-YL)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)benzamido)piperidine-1-carboxylate | HCID 123439813 | — |
| Reagent | Water | HCID 962 | — |
| Reagent | Sodium Hydroxide | HCID 14798 | — |
| Catalyst | [1,1'-bis(di-tert-butylphosphino) ferrocene]dichloropalladium(II) | HCID 86278421 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-butyl (3R)-3-[[4-[5-[2-[(1R)-1-ethoxycarbonyloxyethyl]tetrazol-5-yl]-1-methylpyrazol-4-yl]benzoyl]-(3-methyl-2-pyridinyl)amino]piperidine-1-carboxylate | HCID 117661199 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
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| Source dataset | 39k HTE dataset from Pfizer |
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| ORD ID | ord-f1efc930fc2045d4901e83d436ed6553 |
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| Source note | 39k HTE dataset from Pfizer |
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