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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017201Generated: October 31, 2026

Potassium (4-tert-butoxycarbonylpiperazin-1-yl)methyltrifluoroborate → HCID 178425086, compound

https://huagongshe.com/reaction/2017201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium (4-tert-butoxycarbonylpiperazin-1-yl)methyltrifluoroborateHCID 45588144—
Reactant2-((2-(benzyloxy)-4,6-dimethylpyridin-3-yl)methyl)-7-bromo-5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 86723728—
ReagentWaterHCID 962—
ReagentCesium fluorideHCID 25953—
Catalystpalladium(II) acetateHCID 167845—
CatalystHCID 178454858HCID 178454858—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178425086HCID 178425086—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-08be5cac46434f11bb40c87141158707
Source note39k HTE dataset from Pfizer