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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017288Generated: October 29, 2026

1H-Pyrazole, 4-bromo-1-methyl- → 2-(Pyridin-3-ylmethyl)quinoxaline

https://huagongshe.com/reaction/2017288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Pyrazole, 4-bromo-1-methyl-HCID 167433—
ReactantHCID 178492748HCID 178492748—
ReagentPotassium BicarbonateHCID 516893—
ReagentPotassium t-amylateHCID 23683543—
Catalyst1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
CatalystHCID 178455864HCID 178455864—
SolventDimethyl SulfoxideHCID 679—
Product2-(Pyridin-3-ylmethyl)quinoxalineHCID 162265852—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature130 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-6e5739cda1084f98a74ae2479e8e5779
Source note39k HTE dataset from Pfizer