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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 201737Generated: October 27, 2026

5-Bromo-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amide → 5-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amide

https://huagongshe.com/reaction/201737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amideHCID 61234554—
Reactant3-Ethynyl-7-difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidineHCID 86608081—
Product5-[7-Difluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid bis-(2-hydroxy-ethyl)-amideHCID 67001213—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-991a8c6f073347dba19a01b1170874eb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)