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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017598Generated: October 29, 2026

HCID 56655901, compound → HCID 178456409, compound

https://huagongshe.com/reaction/2017598

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 56655901HCID 56655901—
Reactant2-((2-(benzyloxy)-4,6-dimethylpyridin-3-yl)methyl)-7-bromo-5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 86723728—
ReagentWaterHCID 962—
ReagentCesium fluorideHCID 25953—
CatalystDichloro-(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)palladium(II)HCID 60153068—
SolventTolueneHCID 1140—
ProductHCID 178456409HCID 178456409—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3b314185c4a5441b8a0ffde2b60e0003
Source note39k HTE dataset from Pfizer