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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017633Generated: October 29, 2026

HCID 71696867, compound → HCID 178425085, compound

https://huagongshe.com/reaction/2017633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 71696867HCID 71696867—
Reactant2-((2-(benzyloxy)-4,6-dimethylpyridin-3-yl)methyl)-7-bromo-5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 86723728—
ReagentWaterHCID 962—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalyst[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneHCID 75537289—
SolventTolueneHCID 1140—
ProductHCID 178425085HCID 178425085—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-79da1844938940d9902d119feb200833
Source note39k HTE dataset from Pfizer