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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017858Generated: November 2, 2026

(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 178452029, compound

https://huagongshe.com/reaction/2017858

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(+)-1-Boc-3-aminopyrrolidineHCID 854070—
Reactant4-(5-bromopyridin-2-yl)morpholineHCID 10966724—
ReagentPotassium t-amylateHCID 23683543—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-(Di-tert-butylphosphanyl)-1-(2-methoxyphenyl)-1H-pyrroleHCID 46919526—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178452029HCID 178452029—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-7c6fd60e34f0498f80bf3d4c7c16f116
Source note39k HTE dataset from Pfizer