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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2017873Generated: October 29, 2026

(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 178452029, compound

https://huagongshe.com/reaction/2017873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(+)-1-Boc-3-aminopyrrolidineHCID 854070—
Reactant4-(5-bromopyridin-2-yl)morpholineHCID 10966724—
Reagent2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
Catalystpalladium(II) acetateHCID 167845—
CatalystBippyPhosHCID 11547931—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178452029HCID 178452029—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-0933e6559892401a9fc8caa2d91ce279
Source note39k HTE dataset from Pfizer