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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018221Generated: October 29, 2026

Methyl 3-bromoisonicotinate → HCID 178498390, compound

https://huagongshe.com/reaction/2018221

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-bromoisonicotinateHCID 2762700—
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazoleHCID 16414180—
ReagentWaterHCID 962—
ReagentCesium fluorideHCID 25953—
CatalystBis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)HCID 11714597—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178498390HCID 178498390—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-a4944fcd0b054c8f853342c5bc556a2c
Source note39k HTE dataset from Pfizer