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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018253Generated: October 29, 2026

Diboron tetrahydroxide → 1-Methyl-1H-benzoimidazole-6-boronic acid

https://huagongshe.com/reaction/2018253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiboron tetrahydroxideHCID 10986154—
Reactant6-Bromo-1-methyl-1H-benzimidazoleHCID 23537644—
ReagentPotassium AcetateHCID 517044—
Catalystpalladium(II) acetateHCID 167845—
Catalyst1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 636044—
Solvent2-Methyl-2-butanolHCID 6405—
Product1-Methyl-1H-benzoimidazole-6-boronic acidHCID 46738679—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-bb828f7655824c8fa01e381f17c15006
Source note39k HTE dataset from Pfizer