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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018290Generated: October 30, 2026

Diboron tetrahydroxide → 1-Methyl-1H-benzoimidazole-6-boronic acid

https://huagongshe.com/reaction/2018290

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiboron tetrahydroxideHCID 10986154—
Reactant6-Bromo-1-methyl-1H-benzimidazoleHCID 23537644—
ReagentSodium BicarbonateHCID 516892—
CatalystTricyclohexylphosphineHCID 75806—
Catalystpalladium(II) acetateHCID 167845—
SolventTetrahydrofuranHCID 8028—
Product1-Methyl-1H-benzoimidazole-6-boronic acidHCID 46738679—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-25c39a4d78d947e3b58d9cf6641c5285
Source note39k HTE dataset from Pfizer