Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018322Generated: October 29, 2026

Diboron tetrahydroxide → 1-Methyl-1H-benzoimidazole-6-boronic acid

https://huagongshe.com/reaction/2018322

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiboron tetrahydroxideHCID 10986154—
Reactant6-Bromo-1-methyl-1H-benzimidazoleHCID 23537644—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-(Dicyclohexylphosphino)biphenylHCID 2734216—
SolventAcetonitrileHCID 6342—
Product1-Methyl-1H-benzoimidazole-6-boronic acidHCID 46738679—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-14be6ad26bf14355acfdca90904a96b7
Source note39k HTE dataset from Pfizer