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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018537Generated: October 29, 2026

1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → HCID 178481784, compound

https://huagongshe.com/reaction/2018537

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 4912908—
Reactant5-Chloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 18369506—
ReagentWaterHCID 962—
ReagentSodium BicarbonateHCID 516892—
CatalystDichlorobis(triphenylphosphine)palladiumHCID 6102075—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178481784HCID 178481784—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-49a1af0fc9484948b725d685bf79d381
Source note39k HTE dataset from Pfizer