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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018541Generated: October 29, 2026

1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → HCID 178481784, compound

https://huagongshe.com/reaction/2018541

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 4912908—
Reactant5-Chloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 18369506—
ReagentCesium fluorideHCID 25953—
Catalystpalladium(II) acetateHCID 167845—
CatalystHCID 178454858HCID 178454858—
SolventAcetonitrileHCID 6342—
ProductHCID 178481784HCID 178481784—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-83333f156461409eb5cb5650cd72dce3
Source note39k HTE dataset from Pfizer