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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018653Generated: October 30, 2026

2-Bromo-5-methoxypyridine → HCID 178490386, compound

https://huagongshe.com/reaction/2018653

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-methoxypyridineHCID 11148151—
Reactantpotassium tert-butyl N-(2-(trifluoroboranuidyl)ethyl)carbamateHCID 42614635—
ReagentWaterHCID 962—
ReagentCesium carbonateHCID 10796—
CatalystNaphthoquinone-1,3-bis(2,4,6-trimethylphenyl)-imidazole-2-ylidenepalladium(0), CX 12HCID 11815667—
SolventWaterHCID 962—
SolventTolueneHCID 1140—
ProductHCID 178490386HCID 178490386—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-64918dd861344390a03c211d7847ddd2
Source note39k HTE dataset from Pfizer