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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018672Generated: October 29, 2026

Methyl 3,5-Dibromobenzoate → Methyl-3-bromo-5-(3-pyridyl)benzoate

https://huagongshe.com/reaction/2018672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3,5-DibromobenzoateHCID 621923—
Reactant3-Pyridinylboronic acidHCID 2734378—
ReagentCesium fluorideHCID 25953—
Catalyst[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneHCID 75537289—
SolventTetrahydrofuranHCID 8028—
ProductMethyl-3-bromo-5-(3-pyridyl)benzoateHCID 21942604—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-a5308c3676844e5f83e1f8417de184fe
Source note39k HTE dataset from Pfizer