HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2018898Generated: November 1, 2026
2-Bromophenetole → tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate
https://huagongshe.com/reaction/2018898
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Bromophenetole | HCID 68500 | — |
| Reactant | (R)-1-Boc-3-hydroxypiperidine | HCID 1514398 | — |
| Reagent | Lithium Hexamethyldisilazide | HCID 2733832 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | Di-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphane | HCID 11618717 | — |
| Solvent | 2-Methyl-2-butanol | HCID 6405 | — |
| Product | tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate | HCID 131737068 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-7160d99bc58448bf929e05d989fb5757 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
