HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2019130Generated: October 29, 2026
Benzene, 1-ethoxy-2-iodo- → tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate
https://huagongshe.com/reaction/2019130
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzene, 1-ethoxy-2-iodo- | HCID 136415 | — |
| Reactant | (R)-1-Boc-3-hydroxypiperidine | HCID 1514398 | — |
| Reagent | Cesium carbonate | HCID 10796 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | Di-tert-butyl(2',4',6'-tris(propan-2-yl)-(1,1'-biphenyl)-2-yl)phosphane | HCID 11618717 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | tert-butyl (R)-3-(2-ethoxyphenoxy)piperidine-1-carboxylate | HCID 131737068 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-2a99200d9d2743d1a75212daaef675c9 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
