HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2019912Generated: October 29, 2026
1,4-Dimethyl-1H-1,2,3-triazole → 5-bromo-8-chloro-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-3,4-dihydroisoquinolin-1(2H)-one
https://huagongshe.com/reaction/2019912
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dimethyl-1H-1,2,3-triazole | HCID 15257142 | — |
| Reactant | 5-bromo-8-chloro-7-iodo-3,4-dihydroisoquinolin-1(2H)-one | HCID 118572023 | — |
| Reagent | Sodium Bicarbonate | HCID 516892 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Catalyst | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Solvent | 2-Methyl-2-butanol | HCID 6405 | — |
| Product | 5-bromo-8-chloro-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-3,4-dihydroisoquinolin-1(2H)-one | HCID 86723830 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-a2c5142f9d57422ab78fe5e97fb60867 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
