HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2020261Generated: October 30, 2026
Methyl Acrylate → (E)-methyl 3-(3,5-difluoro-4-formylphenyl)acrylate
https://huagongshe.com/reaction/2020261
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl Acrylate | HCID 7294 | — |
| Reactant | 4-Bromo-2,6-difluorobenzaldehyde | HCID 2773290 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Lithium Chloride | HCID 433294 | — |
| Catalyst | Tri-o-tolylphosphine | HCID 80271 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (E)-methyl 3-(3,5-difluoro-4-formylphenyl)acrylate | HCID 117719453 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-0840634c7e254c918574faec0160bc77 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
