Ethyl(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate → Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

HRID 20207Notes

Reaction equation

HRID 20207 reaction equation
N1C2C(=CC=CN=2)C(C(=O)C([O-])=O)=C1.[K+:15].C([O:18][C:19](=[O:35])[C:20]([C:22]1[C:30]2[C:25](=[C:26]([O:33][CH3:34])[N:27]=[CH:28][C:29]=2[O:31][CH3:32])[NH:24][CH:23]=1)=[O:21])C>>[CH3:32][O:31][C:29]1[CH:28]=[N:27][C:26]([O:33][CH3:34])=[C:25]2[C:30]=1[C:22]([C:20](=[O:21])[C:19]([O-:35])=[O:18])=[CH:23][NH:24]2.[K+:15]

Participants

3

Reactant 2

HCID 22893828Ethyl(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetateHCID 23721194Alfa-oxo-1H-pyrrolo-[2,3B]pyridine-3-acetic acid monopotassium salt

Product 1

HCID 22893810Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate

Procedure

Compound 3ao (Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate) was prepared (as a yellow solid), by the same method used to prepare compound 3a except Ethyl(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate was employed as the starting material. MS m/z: (M+H)+ of the corresponding acid of compound 3ao (M−K+H)+ calcd for C11H11N2O5: 251.07; found 251.09. HPLC retention time: 0.69 minutes (column B).

Sources & evidence

ORD record
ord-a201821648944aa6af05ff138c15deb8
Source dataset
uspto-grants-2010_06
Patent number
US07745625B2

Reaction notes

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