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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 202086Generated: October 26, 2026

Dimethyl Sulfoxide → 4-N-[5-chloro-4-[3-chloro-6-(oxan-4-ylmethylamino)-2-pyridinyl]-2-pyridinyl]-1-N-(3,3,3-trifluoro-2-methoxypropyl)cyclohexane-1,4-diamine

https://huagongshe.com/reaction/202086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
Reactant2,6-LutidineHCID 7937—
Reactant3,5'-dichloro-2'-fluoro-N-((tetrahydro-2H-pyran-4-yl)methyl)-2,4'-bipyridin-6-amineHCID 58127159—
Reactant4-N-(3,3,3-trifluoro-2-methoxypropyl)cyclohexane-1,4-diamineHCID 66937259—
Product4-N-[5-chloro-4-[3-chloro-6-(oxan-4-ylmethylamino)-2-pyridinyl]-2-pyridinyl]-1-N-(3,3,3-trifluoro-2-methoxypropyl)cyclohexane-1,4-diamineHCID 77201419—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-d7a1ad66f3df4624905c9e4dbdf1ec54
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)