Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2021869Generated: October 30, 2026

Methyl propiolate → HCID 121599062, compound

https://huagongshe.com/reaction/2021869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl propiolateHCID 13536—
Reactant5-BromopyrimidineHCID 78344—
ReagentDiisopropylethylamineHCID 81531—
ReagentCopper(I) iodideHCID 6432705—
Catalyst[1,1-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichlormethaneHCID 75537289—
SolventDimethylformamideHCID 6228—
ProductHCID 121599062HCID 121599062—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3112708f3bc04b6abe56f24b96c14756
Source note39k HTE dataset from Pfizer